Performance enhancing drug?

While it will probably surprise no one who watches a lot of baseball, I stumbled onto something I hadn’t known before.

Nicotine has been shown in a scientific study to enhance athletic performance:

Nicotine is widely reported to increase alertness, improve co-ordination and enhance cognitive performance; however, to our knowledge there have been no attempts to replicate these findings in relation to exercise endurance. The purpose of this study was to determine the effects nicotine might have on cycling endurance, perception of exertion and a range of physiological variables. With local ethics committee approval and having obtained informed consent, 12 healthy, non-smoking men (22 ± 3 years; maximal O₂ uptake, 56 ± 6 ml kg^?1 min^?1, mean ± s.d.) cycled to exhaustion at 18°C and 65% of their peak aerobic power, wearing either a 7 mg transdermal nicotine patch (NIC) or a colour-matched placebo (PLA) in a randomized cross-over design; water was available ad libitum. Subjects were exercising at approximately 75% of their maximal O₂ uptake with no differences in cadence between trials. Ten out of 12 subjects cycled for longer with NIC administration, and this resulted in a significant 17 ± 7% improvement in performance (P < 0.05). No differences were observed for perceived exertion, heart rate or ventilation. There were no differences in concentrations of plasma glucose, lactate or circulating fatty acids. In the absence of any effect on peripheral markers, we conclude that nicotine prolongs endurance by a central mechanism. Possible modes of action are suggested.

It certainly improves concentration, and I wonder whether that accounts for the improved athletic performance.

I am sure this sort of evidence will be another argument for banning its use by athletes, but I find myself wondering about its use on the job. If it enhances performance, it ought to be embraced wholeheartedly by employers. If a nicotine break improves productivity, perhaps tobacco-using workers shouldn’t be so stigmatized.