This is very bad news:

Pakistan opposition leader Benazir Bhutto has died after a suicide attack at a political rally.
She was shot in the chest and neck shortly after her speech in Rawalpindi, Pakistan.
Ms Bhutto was attacked as she got into her car and the gunman then blew himself up.
“At 6.16 p.m. she expired,” said Wasif Ali Khan, a member of Bhutto’s party at Rawalpindi General Hospital.
“She has been martyred,” said party offical Rehman Malik.
The explosion went off just after Ms Bhutto left the rally in Rawalpindi, minutes after her speech to thousands of people.
Her supports have smashed windows at the entrance to the hospital where she was being treated, some calling “Dog, Musharraf, dog,”.
It is the first major attack since President General Pervez Musharraf lifted emergency rule two weeks ago.

It not only does not bode well for democracy in Pakistan, but by highlighting the growing instability of a nuclear power, it’s a reminder that isolationism — whether of the Ron Paul, Pat Buchanan, or Dennis Kucinich varieties — is not a great idea.
I hope cool heads prevail.
(There have to be cool heads over there, right?)
MORE: Al Qaeda is reportedly claiming credit for the assassination — a claim U.S. intel officials are checking out.
AND MORE: Glenn Reynolds and Pajamas Media have roundups of reports and reactions.
While it’s too early to predict, this could have very serious consequences.